All eyes will be on Marcus Rashford, who has been in terrific form, scoring 27 goals across all competitions. And if the England international remains on song then a last-four berth should be well within reach.
Meanwhile, Marco Silva’s Fulham head into this fixture after receiving a 3-0 thrashing from Premier League leaders Arsenal. A quarter-final berth is Fulham’s best run in the FA Cup since the 2009-10 season, and it has been over two decades since they reached the semifinals in 2001-02.
United have won each of their last eight FA Cup games against Fulham, which is not encouraging for the cottagers.
How to watch Man Utd vs Fulham on TV & live stream online
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In the United States (US), the game can be watched live on ESPN+
ITV1 and STV will showcase the game in the United Kingdom (UK), with streaming available on ITVX and STV Player.
In India, the Sony Sports network has the rights to show FA Cup games with streaming on SonyLIV.
Man Utd team news & squad
Casemiro remains suspended while Alejandro Garnacho and Anthony Martial are injured. Whereas, Antony remains doubtful with illness along with Scott McTominay.
Donny van de Beek and Christian Eriksen are long-term absentees.
Man Utd possible XI: De Gea; Dalot, Varane, Martinez, Shaw; Fred, Sabitzer; Sancho, Fernandes, Rashford; Weghorst
Fulham team news & squad
Joao Palhinha is coming back from his two-match ban. However, Layvin Kurzawa and Neeskens Kebano remain absent.
But they will be boosted with the return of Willian, Tom Cairney, and Cedric Soares who could not feature against his parent-club Arsenal in their last outing.
Fulham possible XI: Rodak; Tete, Diop, Ream, Robinson; Palhinha, Reed; Willian, Pereira, Solomon; Mitrovic